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Thioredoxin regulates the redox state and the activity of the human tRNA ligase complex
The mammalian tRNA ligase complex (tRNA-LC) catalyzes the splicing of intron-containing pre-tRNAs in the nucleus and the splicing of XBP1 mRNA during the unfolded protein response (UPR) in the cytoplasm. We recently reported that the tRNA-LC coevolved with PYROXD1, an essential oxidoreductase that p...
Autores principales: | Jaksch, Dhaarsini, Irnstorfer, Johanna, Kalman, Petra-Franziska, Martinez, Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653391/ https://www.ncbi.nlm.nih.gov/pubmed/37648453 http://dx.doi.org/10.1261/rna.079732.123 |
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