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Whole blood RNA extraction efficiency contributes to variability in RNA sequencing data sets
Numerous methodologies are used for blood RNA extraction, and large quantitative differences in recovered RNA content are reported. We evaluated three archived data sets to determine how extraction methodologies might influence mRNA and lncRNA sequencing results. The total quantity of RNA recovered...
Autores principales: | Wilfinger, William W., Eghbalnia, Hamid R., Mackey, Karol, Miller, Robert, Chomczynski, Piotr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653446/ https://www.ncbi.nlm.nih.gov/pubmed/37972054 http://dx.doi.org/10.1371/journal.pone.0291209 |
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