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PGP-14 establishes a polar lipid permeability barrier within the C. elegans pharyngeal cuticle
The cuticles of ecdysozoan animals are barriers to material loss and xenobiotic insult. Key to this barrier is lipid content, the establishment of which is poorly understood. Here, we show that the p-glycoprotein PGP-14 functions coincidently with the sphingomyelin synthase SMS-5 to establish a pola...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653525/ https://www.ncbi.nlm.nih.gov/pubmed/37930961 http://dx.doi.org/10.1371/journal.pgen.1011008 |