PGP-14 establishes a polar lipid permeability barrier within the C. elegans pharyngeal cuticle

The cuticles of ecdysozoan animals are barriers to material loss and xenobiotic insult. Key to this barrier is lipid content, the establishment of which is poorly understood. Here, we show that the p-glycoprotein PGP-14 functions coincidently with the sphingomyelin synthase SMS-5 to establish a pola...

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Detalles Bibliográficos
Autores principales: Kamal, Muntasir, Tokmakjian, Levon, Knox, Jessica, Han, Duhyun, Moshiri, Houtan, Magomedova, Lilia, Nguyen, Ken CQ, Zheng, Hong, Burns, Andrew R., Cooke, Brittany, Lacoste, Jessica, Yeo, May, Hall, David H., Cummins, Carolyn L., Roy, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653525/
https://www.ncbi.nlm.nih.gov/pubmed/37930961
http://dx.doi.org/10.1371/journal.pgen.1011008

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