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Alignment-based Protein Mutational Landscape Prediction: Doing More with Less

The wealth of genomic data has boosted the development of computational methods predicting the phenotypic outcomes of missense variants. The most accurate ones exploit multiple sequence alignments, which can be costly to generate. Recent efforts for democratizing protein structure prediction have ov...

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Detalles Bibliográficos
Autores principales: Abakarova, Marina, Marquet, Céline, Rera, Michael, Rost, Burkhard, Laine, Elodie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653582/
https://www.ncbi.nlm.nih.gov/pubmed/37936309
http://dx.doi.org/10.1093/gbe/evad201