Cargando…
Alignment-based Protein Mutational Landscape Prediction: Doing More with Less
The wealth of genomic data has boosted the development of computational methods predicting the phenotypic outcomes of missense variants. The most accurate ones exploit multiple sequence alignments, which can be costly to generate. Recent efforts for democratizing protein structure prediction have ov...
Autores principales: | Abakarova, Marina, Marquet, Céline, Rera, Michael, Rost, Burkhard, Laine, Elodie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653582/ https://www.ncbi.nlm.nih.gov/pubmed/37936309 http://dx.doi.org/10.1093/gbe/evad201 |
Ejemplares similares
-
Manage more by doing less
por: Loen, Raymond O
Publicado: (1971) -
Less is more, but are we doing enough?
por: Ñamendys-Silva, Silvio A.
Publicado: (2019) -
Embeddings from protein language models predict conservation and variant effects
por: Marquet, Céline, et al.
Publicado: (2021) -
Existing trial data do not support that hydroxyethyl starch is less harmful when given on more ‘correct’ indications
por: Haase, Nicolai, et al.
Publicado: (2013) -
SNAP predicts effect of mutations on protein function
por: Bromberg, Yana, et al.
Publicado: (2008)