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NK cell exhaustion in the tumor microenvironment

Natural killer (NK) cells kill mutant cells through death receptors and cytotoxic granules, playing an essential role in controlling cancer progression. However, in the tumor microenvironment (TME), NK cells frequently exhibit an exhausted status, which impairs their immunosurveillance function and...

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Detalles Bibliográficos
Autores principales: Jia, Hao, Yang, Hongmei, Xiong, Huaxing, Luo, Kathy Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653587/
https://www.ncbi.nlm.nih.gov/pubmed/38022646
http://dx.doi.org/10.3389/fimmu.2023.1303605