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Genome instability footprint under rapamycin and hydroxyurea treatments

The mutational processes dictating the accumulation of mutations in genomes are shaped by genetic background, environment and their interactions. Accurate quantification of mutation rates and spectra under drugs has important implications in disease treatment. Here, we used whole-genome sequencing a...

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Detalles Bibliográficos
Autores principales: Li, Jing, Stenberg, Simon, Yue, Jia-Xing, Mikhalev, Ekaterina, Thompson, Dawn, Warringer, Jonas, Liti, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653606/
https://www.ncbi.nlm.nih.gov/pubmed/37931001
http://dx.doi.org/10.1371/journal.pgen.1011012