Recent progress in discovery of novel AAK1 inhibitors: from pain therapy to potential anti-viral agents

Adaptor associated kinase 1 (AAK1), a member of the Ark1/Prk1 family of Ser/Thr kinases, is a specific key kinase regulating Thr156 phosphorylation at the μ2 subunit of the adapter complex-2 (AP-2) protein. Due to their important biological functions, AAK1 systems have been validated in clinics for...

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Detalles Bibliográficos
Autores principales: Yuan, Ying-Hui, Mao, Nian-Dong, Duan, Ji-Long, Zhang, Hang, Garrido, Carmen, Lirussi, Frédéric, Gao, Yuan, Xie, Tian, Ye, Xiang-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653628/
https://www.ncbi.nlm.nih.gov/pubmed/37955299
http://dx.doi.org/10.1080/14756366.2023.2279906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653628/
https://www.ncbi.nlm.nih.gov/pubmed/37955299
http://dx.doi.org/10.1080/14756366.2023.2279906

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