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Conserved metabolic regulator ArcA responds to oxygen availability, iron limitation, and cell envelope perturbations during bacteremia
Gram-negative facultative anaerobes often cause bacteremia, a systemic infection associated with severe clinical outcomes. ArcAB, a two-component regulatory system that represses aerobic respiration, is a key mediator of metabolic adaptation for such bacteria. Using targeted mutational analysis info...
Autores principales: | Brown, Aric N., Anderson, Mark T., Smith, Sara N., Bachman, Michael A., Mobley, Harry L. T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653796/ https://www.ncbi.nlm.nih.gov/pubmed/37681955 http://dx.doi.org/10.1128/mbio.01448-23 |
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