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Functional diversification despite structural congruence in the HipBST toxin-antitoxin system of Legionella pneumophila

Toxin-antitoxin (TA) systems are abundant genetic modules in bacterial chromosomes and on mobile elements. They are often patchily distributed, as a consequence of horizontal exchange, and the breadth of their functionality in bacterial physiology remains unknown. Here, we characterize a TA system i...

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Detalles Bibliográficos
Autores principales: Lin, Jordan D., Stogios, Peter J., Abe, Kento T., Wang, Avril, MacPherson, John, Skarina, Tatiana, Gingras, Anne-Claude, Savchenko, Alexei, Ensminger, Alexander W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653801/
https://www.ncbi.nlm.nih.gov/pubmed/37819088
http://dx.doi.org/10.1128/mbio.01510-23