Human GBP1 facilitates the rupture of the Legionella-containing vacuole and inflammasome activation

The inflammasome is essential for host defense against intracellular bacterial pathogens, including Legionella pneumophila, the causative agent of the severe pneumonia Legionnaires’ disease. Inflammasomes recruit and activate caspases, which promote IL-1 family cytokine release and pyroptosis to res...

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Detalles Bibliográficos
Autores principales: Bass, Antonia R., Egan, Marisa S., Alexander-Floyd, Jasmine, Lopes Fischer, Natasha, Doerner, Jessica, Shin, Sunny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653807/
https://www.ncbi.nlm.nih.gov/pubmed/37737612
http://dx.doi.org/10.1128/mbio.01707-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653807/
https://www.ncbi.nlm.nih.gov/pubmed/37737612
http://dx.doi.org/10.1128/mbio.01707-23

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