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Human GBP1 facilitates the rupture of the Legionella-containing vacuole and inflammasome activation
The inflammasome is essential for host defense against intracellular bacterial pathogens, including Legionella pneumophila, the causative agent of the severe pneumonia Legionnaires’ disease. Inflammasomes recruit and activate caspases, which promote IL-1 family cytokine release and pyroptosis to res...
Autores principales: | Bass, Antonia R., Egan, Marisa S., Alexander-Floyd, Jasmine, Lopes Fischer, Natasha, Doerner, Jessica, Shin, Sunny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653807/ https://www.ncbi.nlm.nih.gov/pubmed/37737612 http://dx.doi.org/10.1128/mbio.01707-23 |
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