The Adr1 transcription factor directs regulation of the ergosterol pathway and azole resistance in Candida albicans

Transcription factors (TFs) play key roles in cellular regulation and are critical in the control of drug resistance in the fungal pathogen Candida albicans. We found that activation of the transcription factor C4_02500C_A (Adr1) conferred significant resistance against fluconazole. In Saccharomyces...

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Detalles Bibliográficos
Autores principales: Shrivastava, Manjari, Kouyoumdjian, Gaëlle S., Kirbizakis, Eftyhios, Ruiz, Daniel, Henry, Manon, Vincent, Antony T., Sellam, Adnane, Whiteway, Malcolm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653825/
https://www.ncbi.nlm.nih.gov/pubmed/37791798
http://dx.doi.org/10.1128/mbio.01807-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653825/
https://www.ncbi.nlm.nih.gov/pubmed/37791798
http://dx.doi.org/10.1128/mbio.01807-23

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