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The Adr1 transcription factor directs regulation of the ergosterol pathway and azole resistance in Candida albicans
Transcription factors (TFs) play key roles in cellular regulation and are critical in the control of drug resistance in the fungal pathogen Candida albicans. We found that activation of the transcription factor C4_02500C_A (Adr1) conferred significant resistance against fluconazole. In Saccharomyces...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653825/ https://www.ncbi.nlm.nih.gov/pubmed/37791798 http://dx.doi.org/10.1128/mbio.01807-23 |