M2a macrophages facilitate resolution of chemically-induced colitis in TLR4-SNP mice

Toll-like receptor 4 (TLR4) is an innate immune receptor responsive to lipopolysaccharide (LPS). Single nucleotide polymorphisms (SNPs) in human TLR4 that encode an A896G transition at SNP rs4986790 (D299G) and a C1196T transition at SNP rs4986791 (T399I) render individuals hyporesponsive to LPS. In...

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Detalles Bibliográficos
Autores principales: Vlk, Alexandra M., Prantner, Daniel, Shirey, Kari Ann, Perkins, Darren J., Buzza, Marguerite S., Thumbigere-Math, Vivek, Keegan, Achsah D., Vogel, Stefanie N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653841/
https://www.ncbi.nlm.nih.gov/pubmed/37768050
http://dx.doi.org/10.1128/mbio.01208-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653841/
https://www.ncbi.nlm.nih.gov/pubmed/37768050
http://dx.doi.org/10.1128/mbio.01208-23

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