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GBS hyaluronidase mediates immune suppression in a TLR2/4- and IL-10-dependent manner during pregnancy-associated infection

Bacterial infections remain a significant cause of adverse pregnancy outcomes. Ascending infection of group B streptococcus (GBS) or Streptococcus agalactiae from the lower genital tract to the amniotic cavity leads to fetal injury, preterm births, or stillbirths. Factors increasing the invasive pot...

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Detalles Bibliográficos
Autores principales: Coleman, Michelle, Orvis, Austyn, Brokaw, Alyssa, Furuta, Anna, Sharma, Kavita, Quach, Phoenicia, Bhullar, Avneet, Sanghavi, Rhea, Nguyen, Shayla, Sweeney, Erin, Seepersaud, Ravin, Armistead, Blair, Adams Waldorf, Kristina M., Rajagopal, Lakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653848/
https://www.ncbi.nlm.nih.gov/pubmed/37747229
http://dx.doi.org/10.1128/mbio.02049-23