Klebsiella phage KP34gp57 capsular depolymerase structure and function: from a serendipitous finding to the design of active mini-enzymes against K. pneumoniae

Virion-associated depolymerases are large trimeric and multi-domain proteins that constitute the phage arsenal to degrade the polysaccharide layers in their bacterial host. Thus, as recombinant proteins, they are endowed with huge potential in biotechnology and medicine. In this study, we elucidated...

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Detalles Bibliográficos
Autores principales: Maciejewska, Barbara, Squeglia, Flavia, Latka, Agnieszka, Privitera, Mario, Olejniczak, Sebastian, Switala, Paulina, Ruggiero, Alessia, Marasco, Daniela, Kramarska, Eliza, Drulis-Kawa, Zuzanna, Berisio, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653864/
https://www.ncbi.nlm.nih.gov/pubmed/37707438
http://dx.doi.org/10.1128/mbio.01329-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653864/
https://www.ncbi.nlm.nih.gov/pubmed/37707438
http://dx.doi.org/10.1128/mbio.01329-23

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