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Klebsiella phage KP34gp57 capsular depolymerase structure and function: from a serendipitous finding to the design of active mini-enzymes against K. pneumoniae
Virion-associated depolymerases are large trimeric and multi-domain proteins that constitute the phage arsenal to degrade the polysaccharide layers in their bacterial host. Thus, as recombinant proteins, they are endowed with huge potential in biotechnology and medicine. In this study, we elucidated...
Autores principales: | Maciejewska, Barbara, Squeglia, Flavia, Latka, Agnieszka, Privitera, Mario, Olejniczak, Sebastian, Switala, Paulina, Ruggiero, Alessia, Marasco, Daniela, Kramarska, Eliza, Drulis-Kawa, Zuzanna, Berisio, Rita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653864/ https://www.ncbi.nlm.nih.gov/pubmed/37707438 http://dx.doi.org/10.1128/mbio.01329-23 |
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