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Low-density hepatitis C virus infectious particles are protected from oxidation by secreted cellular proteins

Hepatitis C virus (HCV) particles secreted from cells are stable at 37°C, whether the producer cell media contain serum or not. Yet, we found that intracellular HCV particles harvested after freeze-thawing of producer cells are highly unstable upon resuspension in a serum-free medium, indicating tha...

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Detalles Bibliográficos
Autores principales: Granier, Christelle, Toesca, Johan, Mialon, Chloé, Ritter, Maureen, Freitas, Natalia, Boson, Bertrand, Pécheur, Eve-Isabelle, Cosset, François-Loïc, Denolly, Solène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653866/
https://www.ncbi.nlm.nih.gov/pubmed/37671888
http://dx.doi.org/10.1128/mbio.01549-23