Polyphosphate uses mTOR, pyrophosphate, and Rho GTPase components to potentiate bacterial survival in Dictyostelium

Human macrophages and the eukaryotic microbe Dictyostelium discoideum ingest bacteria by phagocytosis, and then kill the ingested bacteria. Some pathogenic bacteria secrete linear chains of phosphate residues (polyphosphate; polyP), and the polyP prevents some of the phagocytes from killing the inge...

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Detalles Bibliográficos
Autores principales: Rahman, Ryan J., Rijal, Ramesh, Jing, Shiyu, Chen, Te-An, Ismail, Issam, Gomer, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653871/
https://www.ncbi.nlm.nih.gov/pubmed/37754562
http://dx.doi.org/10.1128/mbio.01939-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653871/
https://www.ncbi.nlm.nih.gov/pubmed/37754562
http://dx.doi.org/10.1128/mbio.01939-23

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