Combination of deep XLMS with deep learning reveals an ordered rearrangement and assembly of a major protein component of the vaccinia virion

Vaccinia virus, the prototypical poxvirus and smallpox/monkeypox vaccine, has proven a challenging entity for structural biology, defying many of the approaches leading to molecular and atomic models for other viruses. Via a combination of deep learning and cross-linking mass spectrometry, we have d...

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Detalles Bibliográficos
Autores principales: Mirzakhanyan, Yeva, Jankevics, Andris, Scheltema, Richard A., Gershon, Paul David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653903/
https://www.ncbi.nlm.nih.gov/pubmed/37646531
http://dx.doi.org/10.1128/mbio.01135-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653903/
https://www.ncbi.nlm.nih.gov/pubmed/37646531
http://dx.doi.org/10.1128/mbio.01135-23

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