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Combination of deep XLMS with deep learning reveals an ordered rearrangement and assembly of a major protein component of the vaccinia virion
Vaccinia virus, the prototypical poxvirus and smallpox/monkeypox vaccine, has proven a challenging entity for structural biology, defying many of the approaches leading to molecular and atomic models for other viruses. Via a combination of deep learning and cross-linking mass spectrometry, we have d...
Autores principales: | Mirzakhanyan, Yeva, Jankevics, Andris, Scheltema, Richard A., Gershon, Paul David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653903/ https://www.ncbi.nlm.nih.gov/pubmed/37646531 http://dx.doi.org/10.1128/mbio.01135-23 |
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