Human OTUD6B positively regulates type I IFN antiviral innate immune responses by deubiquitinating and stabilizing IRF3

Elaborate regulation of innate immunity is necessary for the host to effectively respond to invading pathogens. As an important component of antiviral immunity transcription factors, the stability and activity of interferon (IFN) regulatory factor 3 (IRF3) are tightly controlled via multiple post-tr...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Zheng, Hui, Dong, Chunsheng, Xiong, Sidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653906/
https://www.ncbi.nlm.nih.gov/pubmed/37650650
http://dx.doi.org/10.1128/mbio.00332-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653906/
https://www.ncbi.nlm.nih.gov/pubmed/37650650
http://dx.doi.org/10.1128/mbio.00332-23

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