Nectin-3 and shed forms of CSPG4 can serve as epithelial cell receptors for Clostridioides difficile TcdB

Clostridioides difficile is a Gram-positive bacterium that can cause mild to severe diarrhea, inflammation, and colonic tissue damage in animal hosts. Symptoms of the disease can be attributed to the activity of toxin B (TcdB) secreted by C. difficile during infection. TcdB can engage multiple host...

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Detalles Bibliográficos
Autores principales: Childress, Kevin O., Cencer, Caroline S., Tyska, Matthew J., Lacy, D. Borden
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653914/
https://www.ncbi.nlm.nih.gov/pubmed/37747247
http://dx.doi.org/10.1128/mbio.01857-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653914/
https://www.ncbi.nlm.nih.gov/pubmed/37747247
http://dx.doi.org/10.1128/mbio.01857-23

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