Gene duplication, gene loss, and recombination events with variola virus shaped the complex evolutionary path of historical American horsepox-based smallpox vaccines

Vaccinia virus is the active component of all modern smallpox vaccines after the mid-20th century, but it is uncertain to what extent cowpox, vaccinia, and horsepox viruses were used to produce vaccines before then. Genome sequences of six smallpox vaccines used in the United States between 1850 and...

Descripción completa

Detalles Bibliográficos
Autores principales: Souza, Aline R. V., Brinkmann, Annika, Esparza, José, Nitsche, Andreas, Damaso, Clarissa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653919/
https://www.ncbi.nlm.nih.gov/pubmed/37729584
http://dx.doi.org/10.1128/mbio.01887-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653919/
https://www.ncbi.nlm.nih.gov/pubmed/37729584
http://dx.doi.org/10.1128/mbio.01887-23

Ejemplares similares