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Ligand-displaying Escherichia coli cells and minicells for programmable delivery of toxic payloads via type IV secretion systems
Bacterial type IV secretion systems (T4SSs) are highly versatile macromolecular translocators and offer great potential for deployment as delivery systems for therapeutic intervention. One major T4SS subfamily, the conjugation machines, are well-adapted for delivery of DNA cargoes of interest to oth...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653926/ https://www.ncbi.nlm.nih.gov/pubmed/37772866 http://dx.doi.org/10.1128/mbio.02143-23 |