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The cystic fibrosis treatment Trikafta affects the growth, viability, and cell wall of Aspergillus fumigatus biofilms

People with cystic fibrosis (pwCF) commonly test positive for the pathogenic fungus Aspergillus fumigatus, which is associated with a decline in lung function. Trikafta is a recently approved therapy for pwCF that improves quantity and function of the CFTR protein; however, it is not known how Trika...

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Detalles Bibliográficos
Autores principales: Jones, Jane T., Morelli, Kaesi A., Vesely, Elisa M., Puerner, Charles T. S., Pavuluri, Chetan K., Ross, Brandon S., van Rhijn, Norman, Bromley, Michael J., Cramer, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653927/
https://www.ncbi.nlm.nih.gov/pubmed/37830825
http://dx.doi.org/10.1128/mbio.01516-23