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The major role of Listeria monocytogenes folic acid metabolism during infection is the generation of N-formylmethionine

Folic acid and its derivatives (folates) play central roles in one-carbon metabolism, necessary for the synthesis of purines, pyrimidines, and some amino acids. Antifolate drugs are widely used as broad-spectrum antibiotics for bacterial infections, including listeriosis, a disease caused by the fac...

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Detalles Bibliográficos
Autores principales: Feng, Ying, Chang, Shannon K., Portnoy, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653936/
https://www.ncbi.nlm.nih.gov/pubmed/37695058
http://dx.doi.org/10.1128/mbio.01074-23