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Overlooked Candida glabrata petites are echinocandin tolerant, induce host inflammatory responses, and display poor in vivo fitness

Small colony variants are relatively common among some bacterial species and are associated with poor prognosis and recalcitrant infections. Similarly, Candida glabrata—a major intracellular fungal pathogen—produces small and slow-growing respiratory-deficient colonies, termed “petite.” Despite repo...

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Detalles Bibliográficos
Autores principales: Arastehfar, Amir, Daneshnia, Farnaz, Hovhannisyan, Hrant, Fuentes, Diego, Cabrera, Nathaly, Quinteros, Christopher, Ilkit, Macit, Ünal, Nevzat, Hilmioğlu-Polat, Suleyha, Jabeen, Kauser, Zaka, Sadaf, Desai, Jigar V., Lass-Flörl, Cornelia, Shor, Erika, Gabaldon, Toni, Perlin, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653939/
https://www.ncbi.nlm.nih.gov/pubmed/37772846
http://dx.doi.org/10.1128/mbio.01180-23