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A Toxoplasma gondii lipoxygenase-like enzyme is necessary for virulence and changes localization associated with the host immune response

While the asexual cycle of Toxoplasma gondii can occur in any warm-blooded animal, the sexual cycle is restricted to the feline intestine. We previously determined that because cats lack delta-6-desaturase activity in their intestines, they build up excess linoleic acid, which signals T. gondii to u...

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Detalles Bibliográficos
Autores principales: Ramírez-Flores, Carlos J., Erazo Flores, Billy Joel, Tibabuzo Perdomo, Andrés M., Barnes, Katie L., Wilson, Sarah K., Mendoza Cavazos, Carolina, Knoll, Laura J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653942/
https://www.ncbi.nlm.nih.gov/pubmed/37646522
http://dx.doi.org/10.1128/mbio.01279-23