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Systemic application of bone-targeting peptidoglycan hydrolases as a novel treatment approach for staphylococcal bone infection
The current standard of treatment for chronic staphylococcal osteomyelitis entails high doses of antibiotics over the course of several weeks. Biofilm-associated and intracellular persisters are key factors contributing to therapeutic failure. Additionally, systemic application results in low concen...
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653945/ https://www.ncbi.nlm.nih.gov/pubmed/37768041 http://dx.doi.org/10.1128/mbio.01830-23 |