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ZIKV induction of tristetraprolin in endothelial and Sertoli cells post-transcriptionally inhibits IFNβ/λ expression and promotes ZIKV persistence

Zika virus (ZIKV) is a mosquito-borne Flavivirus that persistently infects patients; enters protected brain, placental, and testicular compartments; is sexually transmitted; and causes fetal microcephaly in utero. ZIKV persistently infects human brain microvascular endothelial cells (hBMECs) that fo...

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Detalles Bibliográficos
Autores principales: Schutt, William R., Conde, Jonas N., Mladinich, Megan C., Himmler, Grace E., Mackow, Erich R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653947/
https://www.ncbi.nlm.nih.gov/pubmed/37707056
http://dx.doi.org/10.1128/mbio.01742-23