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Adipose-Derived Mesenchymal Stem Cell Facilitate Hematopoietic Stem Cell Proliferation via the Jagged-1/Notch-1/Hes Signaling Pathway

BACKGROUND: Poor graft function (PGF) is a life-threatening complication following hematopoietic stem cell transplantation (HSCT). Current therapies, such as CD34(+) cell infusion, have shown limited effectiveness. Conversely, mesenchymal stem cells (MSCs) show potential in addressing PGF. Adipose-d...

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Detalles Bibliográficos
Autores principales: Wang, Hongbo, Bi, Xiaojuan, Zhang, Rongyao, Yuan, Hailong, Xu, Jianli, Zhang, Kaile, Qi, Songqing, Zhang, Xue, Jiang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653966/
https://www.ncbi.nlm.nih.gov/pubmed/38020206
http://dx.doi.org/10.1155/2023/1068405