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Functional comparisons of the virus sensor RIG-I from humans, the microbat Myotis daubentonii, and the megabat Rousettus aegyptiacus, and their response to SARS-CoV-2 infection

Bats (order Chiroptera) are a major reservoir for emerging and re-emerging zoonotic viruses. Their tolerance toward highly pathogenic human viruses led to the hypothesis that bats may possess an especially active antiviral interferon (IFN) system. Here, we cloned and functionally characterized the v...

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Detalles Bibliográficos
Autores principales: Schoen, Andreas, Hölzer, Martin, Müller, Marcel A., Wallerang, Kai B., Drosten, Christian, Marz, Manja, Lamp, Benjamin, Weber, Friedemann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653997/
https://www.ncbi.nlm.nih.gov/pubmed/37728614
http://dx.doi.org/10.1128/jvi.00205-23