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Functional comparisons of the virus sensor RIG-I from humans, the microbat Myotis daubentonii, and the megabat Rousettus aegyptiacus, and their response to SARS-CoV-2 infection
Bats (order Chiroptera) are a major reservoir for emerging and re-emerging zoonotic viruses. Their tolerance toward highly pathogenic human viruses led to the hypothesis that bats may possess an especially active antiviral interferon (IFN) system. Here, we cloned and functionally characterized the v...
Autores principales: | Schoen, Andreas, Hölzer, Martin, Müller, Marcel A., Wallerang, Kai B., Drosten, Christian, Marz, Manja, Lamp, Benjamin, Weber, Friedemann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653997/ https://www.ncbi.nlm.nih.gov/pubmed/37728614 http://dx.doi.org/10.1128/jvi.00205-23 |
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