Cargando…

ROR2 homodimerization is sufficient to activate a neuronal Wnt/calcium signaling pathway

Wnt signaling plays a key role in the mature CNS by regulating trafficking of NMDA-type glutamate receptors and intrinsic properties of neurons. The Wnt receptor ROR2 has been identified as a necessary component of the neuronal Wnt5a/Ca(2+) signaling pathway that regulates synaptic and neuronal func...

Descripción completa

Detalles Bibliográficos
Autores principales: Riquelme, Raul, Li, Laura, Gambrill, Abigail, Barria, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654037/
https://www.ncbi.nlm.nih.gov/pubmed/37832874
http://dx.doi.org/10.1016/j.jbc.2023.105350