Butyrate facilitates immune clearance of colorectal cancer cells by suppressing STAT1-mediated PD-L1 expression

OBJECTIVE: Immunotherapy has been proven to improve the prognosis of patients with advanced malignancy but has shown limited efficacy in patients with Colorectal Cancer (CRC). Increasing evidence suggests that butyrate, a bacterial metabolite, enhances the efficacy of cancer therapies by modulating...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Tao, Yuan, Gu, Yuqing, Ma, Qiujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654141/
https://www.ncbi.nlm.nih.gov/pubmed/37931529
http://dx.doi.org/10.1016/j.clinsp.2023.100303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654141/
https://www.ncbi.nlm.nih.gov/pubmed/37931529
http://dx.doi.org/10.1016/j.clinsp.2023.100303

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