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Sericin enhances ammonia detoxification by promotes urea cycle enzyme genes and activates hepatic autophagy in relation to CARD-9/MAPK pathway

Urea cycle is an important metabolic process that initiates in liver mitochondria and converts ammonia to urea. The impairment of ammonia detoxification, both primary and secondary causes, lead to hyperammonemia, a life-threatening condition affecting to the brain. Current treatments are not enough...

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Detalles Bibliográficos
Autores principales: Ampawong, Sumate, Tirawanchai, Napatara, Kanjanapruthipong, Tapanee, Fongsodsri, Kamonpan, Tuentam, Khwanchanok, Isarangkul, Duangnate, Aramwit, Pornanong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654145/
https://www.ncbi.nlm.nih.gov/pubmed/38027599
http://dx.doi.org/10.1016/j.heliyon.2023.e21563