Safety, Tolerability, and Pharmacokinetics of Same-Knee Intra-Articular Injection of Corticosteroid and Lorecivivint Within 7 Days: An Open-Label, Randomized, Parallel-Arm Study

INTRODUCTION: Knee osteoarthritis (OA) is a common painful disorder. Intra-articular (IA) corticosteroid injections are frequently prescribed to treat knee pain. Lorecivivint (LOR), a novel IA cdc2-Like Kinase (CLK)/Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase (DYRK) inhibitor thought...

Descripción completa

Detalles Bibliográficos
Autores principales: Fineman, Mark S., McAlindon, Timothy E., Lattermann, Christian, Swearingen, Christopher J., Kennedy, Sarah, Lopez, Victor A., Simsek, Ismail, Tambiah, Jeyanesh R. S., Yazici, Yusuf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654271/
https://www.ncbi.nlm.nih.gov/pubmed/37902943
http://dx.doi.org/10.1007/s40744-023-00604-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654271/
https://www.ncbi.nlm.nih.gov/pubmed/37902943
http://dx.doi.org/10.1007/s40744-023-00604-7

Ejemplares similares