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Safety, Tolerability, and Pharmacokinetics of Same-Knee Intra-Articular Injection of Corticosteroid and Lorecivivint Within 7 Days: An Open-Label, Randomized, Parallel-Arm Study

INTRODUCTION: Knee osteoarthritis (OA) is a common painful disorder. Intra-articular (IA) corticosteroid injections are frequently prescribed to treat knee pain. Lorecivivint (LOR), a novel IA cdc2-Like Kinase (CLK)/Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase (DYRK) inhibitor thought...

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Detalles Bibliográficos
Autores principales:	Fineman, Mark S., McAlindon, Timothy E., Lattermann, Christian, Swearingen, Christopher J., Kennedy, Sarah, Lopez, Victor A., Simsek, Ismail, Tambiah, Jeyanesh R. S., Yazici, Yusuf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Healthcare 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654271/ https://www.ncbi.nlm.nih.gov/pubmed/37902943 http://dx.doi.org/10.1007/s40744-023-00604-7

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