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Efficient protocol for the differentiation of kidney podocytes from induced pluripotent stem cells, involving the inhibition of mTOR

The mechanistic/mammalian target of rapamycin (mTOR) is involved in a wide range of cellular processes. However, the role of mTOR in podocytes remains unclear. In this study, we aimed to clarify the role of mTOR in podocyte differentiation from human induced pluripotent stem cells (hiPSCs) and to es...

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Detalles Bibliográficos
Autores principales: Yasuda, Masahiro, Kato, Tadashi, Okano, Mai, Yamashita, Hiromi, Matsuoka, Yoshikazu, Shirouzu, Yasumasa, Fujioka, Tatsuya, Hattori, Fumiyuki, Tsuji, Shoji, Kaneko, Kazunari, Hitomi, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654390/
https://www.ncbi.nlm.nih.gov/pubmed/37973990
http://dx.doi.org/10.1038/s41598-023-47087-8