Design and synthesis of chiral DOTA-based MRI contrast agents with remarkable relaxivities

Due to the adverse effects of de-metallation in past concerning FDA-approved gadolinium-based contrast agents (GBCAs), researchers have been focusing on developing safer and more efficient alternatives that could avoid toxicity caused by free gadolinium ions. Herein, two chiral GBCAs, Gd-LS with sul...

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Detalles Bibliográficos
Autores principales: Zhang, Junhui, Dai, Lixiong, He, Li, Bhattarai, Abhisek, Chan, Chun-Ming, Tai, William Chi-Shing, Vardhanabhuti, Varut, Law, Ga-Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654417/
https://www.ncbi.nlm.nih.gov/pubmed/37973896
http://dx.doi.org/10.1038/s42004-023-01050-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654417/
https://www.ncbi.nlm.nih.gov/pubmed/37973896
http://dx.doi.org/10.1038/s42004-023-01050-w

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