Cargando…

Design and synthesis of chiral DOTA-based MRI contrast agents with remarkable relaxivities

Due to the adverse effects of de-metallation in past concerning FDA-approved gadolinium-based contrast agents (GBCAs), researchers have been focusing on developing safer and more efficient alternatives that could avoid toxicity caused by free gadolinium ions. Herein, two chiral GBCAs, Gd-LS with sul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Junhui, Dai, Lixiong, He, Li, Bhattarai, Abhisek, Chan, Chun-Ming, Tai, William Chi-Shing, Vardhanabhuti, Varut, Law, Ga-Lai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654417/ https://www.ncbi.nlm.nih.gov/pubmed/37973896 http://dx.doi.org/10.1038/s42004-023-01050-w

Ejemplares similares

Chiral DOTA chelators as an improved platform for biomedical imaging and therapy applications
por: Dai, Lixiong, et al.
Publicado: (2018)

Photon-Counting CT Material Decomposition in Bone Imaging
por: Bhattarai, Abhisek, et al.
Publicado: (2023)

Polymeric Gd-DOTA amphiphiles form spherical and fibril-shaped nanoparticle MRI contrast agents
por: Randolph, Lyndsay M., et al.
Publicado: (2016)

Differential Impact of COVID-19 on Cancer Diagnostic Services Based on Body Regions: A Public Facility-Based Study in Hong Kong
por: Vardhanabhuti, Varut, et al.
Publicado: (2021)

Chest-Related Imaging Investigations During Multiple Waves of COVID-19 Infection in Hong Kong
por: Ng, Kei Shing, et al.
Publicado: (2021)

Unusual Magnetic Field Responsive Circularly Polarized Luminescence Probes with Highly Emissive Chiral Europium(III) Complexes
por: Zhang, Junhui, et al.
Publicado: (2020)

Lumazine Synthase Protein Nanoparticle-Gd(III)-DOTA Conjugate as a T(1) contrast agent for high-field MRI
por: Song, YoungKyu, et al.
Publicado: (2015)

CT scan AI-aided triage for patients with COVID-19 in China
por: Vardhanabhuti, Varut
Publicado: (2020)

Highly water-dispersible calcium lignosulfonate-capped MnO nanoparticles as a T(1) MRI contrast agent with exceptional colloidal stability, low toxicity and remarkable relaxivity
por: Arian, Mahdi, et al.
Publicado: (2019)

Joint Cancer Segmentation and PI-RADS Classification on Multiparametric MRI Using MiniSegCaps Network
por: Jiang, Wenting, et al.
Publicado: (2023)

Polymerizable Gd(iii) building blocks for the synthesis of high relaxivity macromolecular MRI contrast agents
por: Berki, Thomas R., et al.
Publicado: (2021)

DOTAREM (DOTA)–Gold-Nanoparticles: Design, Spectroscopic Evaluation to Build Hybrid Contrast Agents to Applications in Nanomedecine
por: Khan, Memona, et al.
Publicado: (2022)

Predicting CT-Based Coronary Artery Disease Using Vascular Biomarkers Derived from Fundus Photographs with a Graph Convolutional Neural Network
por: Huang, Fan, et al.
Publicado: (2022)

Pharmacokinetics of Chiral Dendrimer-Triamine-Coordinated Gd-MRI Contrast Agents Evaluated by in Vivo MRI and Estimated by in Vitro QCM
por: Miyake, Yuka, et al.
Publicado: (2015)

Self-supervised region-aware segmentation of COVID-19 CT images using 3D GAN and contrastive learning
por: Shabani, Siyavash, et al.
Publicado: (2022)

Fluorinated hydrogel nanoparticles with regulable fluorine contents and T(2) relaxation times as (19)F MRI contrast agents
por: Duan, Ziwei, et al.
Publicado: (2023)

Semisupervised white matter hyperintensities segmentation on MRI
por: Huang, Fan, et al.
Publicado: (2022)

Contrast agents for hepatic MRI
por: Morana, Giovanni, et al.
Publicado: (2007)

MRI Contrast Agents in Glycobiology
por: Geraldes, Carlos F. G. C., et al.
Publicado: (2022)

The effects of three different contrast agents (Gd-BOPTA, Gd-DTPA, and Gd-DOTA) on brachial plexus magnetic resonance imaging
por: Zhang, Xiaojing, et al.
Publicado: (2021)

Deep learning-based thigh muscle segmentation for reproducible fat fraction quantification using fat–water decomposition MRI
por: Ding, Jie, et al.
Publicado: (2020)

Impact of metallic trace elements on relaxivities of iron-oxide contrast agents
por: Ma, Ji, et al.
Publicado: (2019)

Chiral Organic Chromophoric Systems in the Enhancement of Circularly Polarized Luminescence
por: Wu, Tao, et al.
Publicado: (2021)

MRI Contrast Agents for Pharmacological Research
por: Terreno, Enzo, et al.
Publicado: (2015)

Magnetic Nanomaterials as Contrast Agents for MRI
por: Caspani, Sofia, et al.
Publicado: (2020)

Magnetic Nanoparticles as MRI Contrast Agents
por: Avasthi, Ashish, et al.
Publicado: (2020)

Influence of Oxidation Degree of Graphene Oxide on Its Nuclear Relaxivity and Contrast in MRI
por: Mohanta, Zinia, et al.
Publicado: (2020)

Synthesis and Relaxivity Studies of a DOTA-Based Nanomolecular Chelator Assembly Supported by an Icosahedral Closo-B(12)(2−) -Core for MRI: A Click Chemistry Approach
por: Goswami, Lalit N., et al.
Publicado: (2013)

Towards visceral fat estimation at population scale: correlation of visceral adipose tissue assessment using three-dimensional cross-sectional imaging with BIA, DXA, and single-slice CT
por: Chan, Benjamin, et al.
Publicado: (2023)

Effects of human articular cartilage constituents on simultaneous diffusion of cationic and nonionic contrast agents
por: Bhattarai, Abhisek, et al.
Publicado: (2020)

Innovative multimodal DOTA/NODA nanoparticles for MRI and PET imaging for tumor detection
por: Truillet, Charles, et al.
Publicado: (2014)

Safety of Gadoterate Meglumine (Gd-DOTA) as a Contrast Agent for Magnetic Resonance Imaging: Results of a Post-Marketing Surveillance Study in Japan
por: Ishiguchi, Tsuneo, et al.
Publicado: (2012)

Synthesis of a DOTA-C-glyco bifunctional chelating agent and preliminary in vitro and in vivo study of [(68)Ga]Ga-DOTA-C-glyco-RGD
por: Mangin, Floriane, et al.
Publicado: (2021)

Lanthanide Complexes (Gd(III) and Eu(III)) Based on a DOTA‐TEMPO Platform for Redox Monitoring via Relaxivity
por: Barré, Richard, et al.
Publicado: (2022)

Pulmonary MRI contrast using Surface Quadrupolar Relaxation (SQUARE) of hyperpolarized (83)Kr()
por: Six, Joseph S., et al.
Publicado: (2014)

Remarks on Relaxation and Descent of the Uterus and Bladder in the Puerperal State
por: Roberton, John
Publicado: (1834)

MRI contrast agents: from molecules to particles
por: Laurent, Sophie, et al.
Publicado: (2017)

Correction to: Magnetic Nanoparticles as MRI Contrast Agents
por: Avasthi, Ashish, et al.
Publicado: (2021)

Cyclodextrins: promising scaffolds for MRI contrast agents
por: Sembo-Backonly, Berthe Sandra, et al.
Publicado: (2021)

Mn-Based MRI Contrast Agents: An Overview
por: Henoumont, Céline, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_c2gpplbpsblb4aod7kkttnb12l