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PDZ Peptide of the ZO-1 Protein Significantly Increases UTP-Induced MUC8 Anti-Inflammatory Mucin Overproduction in Human Airway Epithelial Cells

Mucus hyperproduction and hypersecretion are observed often in respiratory diseases. MUC8 is a glycoprotein synthesized by epithelial cells and generally expressed in the respiratory track. However, the physiological mechanism by which extracellular nucleotides induce MUC8 gene expression in human a...

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Detalles Bibliográficos
Autores principales: Seo, Han, Lee, Hyun-Chae, Lee, Ki Chul, Kim, Doosik, Kim, Jiwook, Kang, Donghee, Chung, Hyung-Joo, Cha, Hee-Jae, Kim, Jeongtae, Song, Kyoung Seob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654460/
https://www.ncbi.nlm.nih.gov/pubmed/37750239
http://dx.doi.org/10.14348/molcells.2023.0107