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Differential spatial distribution of HNF4α isoforms during dysplastic progression of intraductal papillary mucinous neoplasms of the pancreas

Hepatocyte Nuclear Factor 4-alpha (HNF4α) comprises a nuclear receptor superfamily of ligand-dependent transcription factors that yields twelve isoforms in humans, classified into promoters P1 or P2-associated groups with specific functions. Alterations in HNF4α isoforms have been associated with tu...

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Detalles Bibliográficos
Autores principales: Wong, Jahg, Trinh, Vincent Q., Jyotsana, Nidhi, Baig, Jumanah F., Revetta, Frank, Shi, Chanjuan, Means, Anna L., DelGiorno, Kathleen E., Tan, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654504/
https://www.ncbi.nlm.nih.gov/pubmed/37974020
http://dx.doi.org/10.1038/s41598-023-47238-x