A cleavable chimeric peptide with targeting and killing domains enhances LPS neutralization and antibacterial properties against multi-drug resistant E. coli

Pathogenic Escherichia coli is one of the most common causes of diarrhea diseases and its characteristic component of the outer membrane-lipopolysaccharide (LPS) is a major inducer of sepsis. Few drugs have been proven to kill bacteria and simultaneously neutralize LPS toxicity. Here, the chimeric p...

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Detalles Bibliográficos
Autores principales: Wang, Zhenlong, Teng, Da, Mao, Ruoyu, Hao, Ya, Yang, Na, Wang, Xiumin, Wang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654507/
https://www.ncbi.nlm.nih.gov/pubmed/37973936
http://dx.doi.org/10.1038/s42003-023-05528-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654507/
https://www.ncbi.nlm.nih.gov/pubmed/37973936
http://dx.doi.org/10.1038/s42003-023-05528-0

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