SND1 binds to ERG and promotes tumor growth in genetic mouse models of prostate cancer

SND1 and MTDH are known to promote cancer and therapy resistance, but their mechanisms and interactions with other oncogenes remain unclear. Here, we show that oncoprotein ERG interacts with SND1/MTDH complex through SND1’s Tudor domain. ERG, an ETS-domain transcription factor, is overexpressed in m...

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Detalles Bibliográficos
Autores principales: Liao, Sheng-You, Rudoy, Dmytro, Frank, Sander B., Phan, Luan T., Klezovitch, Olga, Kwan, Julian, Coleman, Ilsa, Haffner, Michael C., Li, Dapei, Nelson, Peter S., Emili, Andrew, Vasioukhin, Valeri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654515/
https://www.ncbi.nlm.nih.gov/pubmed/37973913
http://dx.doi.org/10.1038/s41467-023-43245-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654515/
https://www.ncbi.nlm.nih.gov/pubmed/37973913
http://dx.doi.org/10.1038/s41467-023-43245-8

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