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An industrial procedure for the intestinal permeability enhancement of acyclovir: in-vitro and histological evidence

Acyclovir, an antiviral drug, has low bioavailability due to its low permeability. Consequently, high drug doses and frequent administration are required. This study investigates the use of span 60, at different concentrations, as a granulating agent to enhance drug permeability using an industrial...

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Detalles Bibliográficos
Autores principales: Mady, Omar Y., Thabit, Sara Mohsen, Abo Elnasr, Suzan E., Hedaya, Asmaa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654564/
https://www.ncbi.nlm.nih.gov/pubmed/37973930
http://dx.doi.org/10.1038/s41598-023-47306-2