Specific intracellular retention of circSKA3 promotes colorectal cancer metastasis by attenuating ubiquitination and degradation of SLUG

Our previous study demonstrated that tumor-suppressor circular RNAs (circRNAs) can be specifically secreted outside of colorectal cancer (CRC) cells within exosomes to maintain tumor cell fitness. However, whether tumor-driving circRNAs can be specifically retained in cells to facilitate tumor progr...

Descripción completa

Detalles Bibliográficos
Autores principales: Deng, Jingwen, Liao, Shaoxia, Chen, Chaoyi, Han, Fengyan, Lei, Siqin, Lai, Xuan, Ye, Kehong, Han, Qizheng, E, Fang, Lu, Chao, Lai, Maode, Liu, Fanlong, Zhang, Honghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654574/
https://www.ncbi.nlm.nih.gov/pubmed/37973787
http://dx.doi.org/10.1038/s41419-023-06279-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654574/
https://www.ncbi.nlm.nih.gov/pubmed/37973787
http://dx.doi.org/10.1038/s41419-023-06279-w

Ejemplares similares